Glimepiride is an antidiabetic drug which is one of the third generation sulfonylureas.\nIt belongs to class II, according to the BCS (Biopharmaceutical Classification System), which is\ncharacterized by low solubility and high permeability. The aim of this work was to formulate\nglimepiride as solid dispersion using water-soluble carriers to enhance its aqueous solubility and\nthus enhance its bioavailability. Nine formulations of glimepiride solid dispersion were prepared\nby a solvent evaporation technique using three different carriers............................
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